The effect of subminimal inhibitory concentrations of penicillin on growth rate and haemolysin activity of group G Streptococcus
Mem. Inst. Oswaldo Cruz
;
88(3): 431-4, July-Sept. 1993. tab, graf
Artigo
em Inglês
| LILACS
| ID: lil-148798
ABSTRACT
The influence of the subminimal inhibitory concentrations (1/3 and 1/4 of the MIC) of penicillin on growth rate and on haemolysin production of a strain of group G Streptococcus was studied. It was shown that 1/3 of the MIC almost completely inhibited the bacterial growth, but it was not able to inhibit haemolysin activity in the culture supernate. The generation time of bacteria grown in 1/4 of the MIC was approximately twice longer than that of the control culture. In all cultures, the haemolysin, after being produced (or liberated), reached a peak and decreased to low levels, which could suggest that group G Streptococcus produces some end products of metabolism that are able to inhibit haemolysin activity
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Penicilinas
/
Streptococcus
/
Proteínas Hemolisinas
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
1993
Tipo de documento:
Artigo
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