Prueba de apomorfina: evaluación de la respuesta dopaminérgica en parkinsonismos / Apomorphine test: evaluation of dopaminergic response in Parkinson's disease
Rev. méd. Chile
;
123(3): 326-9, mar. 1995. tab
Artigo
em Espanhol
| LILACS
| ID: lil-151188
ABSTRACT
Apomorphine is a potent dopaminergic agonist that quickly and predictably reverts parkinsonian symptomatology. In 32 patients (18 male) aged 45 to 83 years old (22 with idiopathic parkinsonism and 10 with parkinsonism of other causes), the dopaminergic response to apomorphine after domperidone administration was assessed using the digital skill test and Webster scale. Twenty patients with idiopathic parkinsonism and 1 with parkinsonism of other causes had a positive response to apomorphine. In 44 percent apomorphine had adverse effects. All patients with idiopathic parkinsonism and the only patient with parkinsonism of other causes with a positive apomorphine test had a good response to levodopa therapy. It is concluded that apomorphine test has a 95 percent positive value for idiopathic parkinsonism and is useful diagnostic tool
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Índice:
LILACS (Américas)
Assunto principal:
Doença de Parkinson
/
Apomorfina
/
Receptores Dopaminérgicos
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Espanhol
Revista:
Rev. méd. Chile
Assunto da revista:
Medicina
Ano de publicação:
1995
Tipo de documento:
Artigo
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