The diameter of water pores formed by colicin la in planar lipid bilayers
Braz. j. med. biol. res
; 28(6): 693-8, Jun. 1995. graf
Article
em En
| LILACS
| ID: lil-154940
Biblioteca responsável:
BR1.1
RESUMO
The effective size of colicin Ia channel was tested by a recently described method 9FEMS, Microbiology and Immunology (1992). 105 93-100) in which the nonelectrolyte molecules with different hydrodynamic diameters (0.52 to 5.0nm) were used as molecular tools. We have shown that despite low conductance (55-105 pS at 1.5 MKCl, pH 7.0) the ion channels formed by colicin Ia have a fairly large water pore diameter equal to 1.66-1 1.88nm. The results are discussed in terms of an energetic barrier for ions passing into the channel lumen
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Índice:
LILACS
Assunto principal:
Colicinas
/
Canais Iônicos
/
Bicamadas Lipídicas
Idioma:
En
Revista:
Braz. j. med. biol. res
Assunto da revista:
BIOLOGIA
/
MEDICINA
Ano de publicação:
1995
Tipo de documento:
Article