Canales iónicos en células no excitables / Ion channels in non excitable cells
Medicina (B.Aires)
; 55(5/1): 449-56, 1995. ilus, graf
Article
em Es
| LILACS
| ID: lil-161622
Biblioteca responsável:
BR1.1
RESUMO
Several distinct types of voltage-gated and second-messenger-operated K+, Ca2+, Na+ and Cl- channels exist in electrically non excitable cells such as those of the hematopoietic lineage. In these cells ion channels mediate cellular functions involving intraceiiuiar biochemical responses, rather than rapid electrical signaling. The presence of the channels is required for several basic functions, such as activation, secretion of lymphokines, mitogenesis, the regulation of cell volume and the mechanisms of resistance to chemotherapeutic agents. Here IN we review the patch-clamp method for studying many characteristics of these ionic channels, particularly in blood cells.
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Índice:
LILACS
Assunto principal:
Células-Tronco Hematopoéticas
/
Técnicas de Patch-Clamp
/
Canais Iônicos
Idioma:
Es
Revista:
Medicina (B.Aires)
Assunto da revista:
MEDICINA
Ano de publicação:
1995
Tipo de documento:
Article