Human parvovirus B 19 infection and hydrops fetalis in Rio de Janeiro, Brazil
Mem. Inst. Oswaldo Cruz
;
91(2): 147-51, Mar.-Apr. 1996. tab
Artigo
em Inglês
| LILACS
| ID: lil-174368
RESUMO
Formalin-fixed paraffin embedded lung and liver tissue from 23 cases of non immune hydrops fetalis and five control cases, in which hydrops were due to syphilis (3) and genetics causes (2), were examined for the presence of human parvovirus B19 by DNA hybridisation. Using in situ hybridisation with a biotynilated probe one positive case was detected. Using 32 P-labelled probes in a dot blot assay format, five further positives were obtained. These were all confirmed as positive by a nested polymerase chain reaction assay. Electron microscopy revealed virus in all these five positive cases. The six B19 DNA positive cases of hydrops fetalis were from 1974, 1980, 1987 and 1988, four of which occurred during the second half of the year, confirming the seasonality of the disease.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Parvoviridae
/
Sangue
Tipo de estudo:
Estudo diagnóstico
Limite:
Adulto
/
Humanos
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
1996
Tipo de documento:
Artigo
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