Disolución de cálculos vesiculares een una población de mujeres adultas: ensayo de terapia con lovastatina / Gallstone dissolution in an adult female population: essay with lovastatine therapy

ABSTRACT

There are no chilean reports on gallstone dissolution using oral medications. To measure the proportion of asymptomatic adult women elegible for gallstone dissolution therapy and to test the effectiveness and tolerance of lovastatin for this purpose, three hundred fifty six women working at health care onstitutions were subjected to gallbladder ultrasound examination. Non pregnant women with radiolucent gallstone of less than 2 cm were invited to receive lovastatin 20 mg od and were followed during 6 months. Twenty two women had gallstones and 8 eligible women receive lovastatin therapy. No reduction in stone size was observed in these women. Less than half of asymptomatic women with gallstones are elegible for oral therapy. Lovastatin did not reduce gallstone size after 6 months of therapy