A t(9; 11) translocation in childhood acute mixed leukemia
São Paulo med. j
; São Paulo med. j;114(2): 1127-1130, Mar.-Apr. 1996. ilus
Article
em En
| LILACS
| ID: lil-179665
Biblioteca responsável:
BR1.1
RESUMO
We present the case of a child with acute lymphoid teukemia (ALL) who was morphologically classified as FAB L1 (PAS and peroxidase were negative). Remission was achieved with an ALL-type protocol (GBTLI). Five months after the discontinuation of therapy, the patient presented mixed leukemia (CD10, CD19,CD13 and CD33 were positive) with (9;11) (p21;q23) translocation. Unfortunately, as cytogenetic and immunophenotype studies were not performed at diagnosis, two possibilities could be considered for the relapse; secondarly mixed leukemia with clonal chromosome changes, or mixed leukemia from the beginning.
Texto completo:
1
Índice:
LILACS
Assunto principal:
Translocação Genética
/
Leucemia Aguda Bifenotípica
/
Leucemia-Linfoma Linfoblástico de Células Precursoras
Tipo de estudo:
Guideline
Limite:
Child
/
Humans
/
Male
Idioma:
En
Revista:
São Paulo med. j
Assunto da revista:
Cirurgia Geral
/
Cincia
/
Ginecologia
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MEDICINA
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Ano de publicação:
1996
Tipo de documento:
Article