Asociación de enfermedades del tejido conectivo con implantes mamarios de silicona. Perspectiva actual

RESUMO

This review describes one of the most interesting and current controversies in rheumatology the relationship between silicone implants and diseases of the connective tissue. This association has been consedered since 1964 and more recently scleroderma and systemic lupus have been associated to breast implants. Lately it has been demostrated that silicone is not an inert material, but exert active immunological reactions. Moreover recents reports in the literature describe multiple autoantibodies in such patients (namely anti-nucleolar and anti-centromere) as well as atypical rheumatoid symptoms. Prospective controlled studies investigating such atypical complaints in recipients of silicone implants need to be ascertained.