Elevación asintomática de fosfatasas alcalinas plasmáticas secundaria a hiperfosfatasemia familiar benigna en un paciente / Asymptomatic elevation of alkaline phosphatases secondary to benign familial hyperphosphatasemia in a patient

RESUMO

We report a 33 years old male consulting for abdominal pain. Initial diagnostic work up showed high levels of alkaline phosphatases, that were confirmed in a new blood sample. Using electrophoresis, total alkaline phosphatases were 198 U/l (normal values=30-117) and the bone fraction was 101 U/l (normal values=0-35). Bone scintiscan and endocrinological assessment were normal. One year later, the same values persisted. Studying the family, 3 of 4 brothers had the same alterations in alkaline phosphatases. It was concluded that these subjects had the rare condition known as benign familial hyperphosphatasemia