Multifactorial control of water and saline intake: role of alpha2-adrenoceptors
Braz. j. med. biol. res
;
30(4): 497-502, Apr. 1997. ilus, tab, graf
Artigo
em Inglês
| LILACS
| ID: lil-191388
RESUMO
Water and saline intake is controlled by several mechanisms activated during dehydration. Some mechanisms, such as the production of angiotensin II and unloading of cardiovascular receptors, activate both behaviors, while others, such as the increase in blood osmolality or sodium concentration, activate water, but inhibit saline intake. Aldosterone probably activates only saline intake. Clonidine, an alpha2-adrenergic agonist, inhibits water and saline intake induced by these mechanisms. One model to describe the interactions between these multiple mechanisms is a wire-block diagram, where the brain circuit that controls each intake is represented by a summing point of its respective inhibiting and activating factors. The alpha2-adrenoceptors constitute an inhibitory factor common to both summing points.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Sistema Renina-Angiotensina
/
Cloreto de Sódio
/
Norepinefrina
/
Clonidina
/
Receptores Adrenérgicos alfa 2
/
Agonistas alfa-Adrenérgicos
/
Desidratação
/
Ingestão de Líquidos
Tipo de estudo:
Estudo prognóstico
Limite:
Animais
Idioma:
Inglês
Revista:
Braz. j. med. biol. res
Assunto da revista:
Biologia
/
Medicina
Ano de publicação:
1997
Tipo de documento:
Artigo
/
Congresso e conferência
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