Citodiagnóstico de lesiones focales hepáticas mediante punción con aguja fina dirigida por imágenes / Cytodiagnosis of hepatic focal injuries by punction with fine needle controlled by images

ABSTRACT

Two hundred two aspirates, obtained in 201 patients were studied. Procedures were performed under ultrasound guidance in 77.9 percent of cases and under CT scan guidance in 22.1 percent. Cytological diagnoses was compared with definitive pathological diagnosis in 136 patients and with clinical follow up in 66. Cytology was positive for malignant cells in 81.2 percent of cases, negative for malignant cells in 15.3 percent inconclusive in 1 percent and the sample was inadequate in 2.5 percent. Cytology was false negative for malignant lesions in 17 cases and there were no false positives. It had a sensitivity of 90.6 percent, a specificity of 100 percent, a positive predictive value of 100 percent and a negative predictive value of 55.3 percent. The histological types of malignant lesions were adenocarcinoma in 48.2 percent of cases, hepatocellular carcinoma in 16.5 percent and non specific carcinoma in 20.7 percent. The main sites of the primary tumors were the liver in 24.4 percent of cases, gallbladder and biliary tract in 20.9 percent, intestine in 15,1 percent. Cytological diagnosis of fine needle aspirates of the liver obtained under image guidance are a valuable support in the diagnosis of focal liver lesions