Synaptophysin and neurofilament expression in neurons infected with dengue virus
Arch. med. res
;
25(2): 215-7, 1994. ilus
Artigo
em Inglês
| LILACS
| ID: lil-198810
ABSTRACT
The expression of two genes encoding the neuronal specific proteins synaptophysin and high molecular weigh neurofilaments was investigated in primary cell cultures of embryonic mouse brain infected with dengue virus type 2, using immunocytochemistry and Western blot analysis with monoclonal antibodies. The viral infection leads to a 20-fold induction in the expression of the mentioned synaptogenesis-related proteins. These results suggest a correlation between virus infection and neuropathology of immature neurons in vivo
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Índice:
LILACS (Américas)
Assunto principal:
Sinapses
/
Filamentos Intermediários
/
Western Blotting
/
Vírus da Dengue
/
Flavivirus
/
Neurônios
Limite:
Animais
Idioma:
Inglês
Revista:
Arch. med. res
Assunto da revista:
Medicina
Ano de publicação:
1994
Tipo de documento:
Artigo
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