Nodal radiotherapy in refractory tuberculosis in an AIDS patients
Arch. med. res
;
27(1): 93-5, 1996. ilus
Artigo
em Inglês
| LILACS
| ID: lil-200298
ABSTRACT
A 25-year-old female with transfusion-associated acquired immunodeficiency syndrome (AIDS) treated with zidovudine (AZT) developed cervical lymph node enlargement. The histological study disclosed granulomas and the culture revealed M. tuberculosis. The patient was treated with isoniazid, rifampicin and pirazynamide and the lymphadenomegaly resolved. Five years later, with a CD4 cell count of 245, the lymph node enlargement reappeared, the biopsy and special studies confirming tuberculosis (TB). She was then given cirpofloxacin, azithromicin, ethambutol, amikacin and pirazyn amide without success. In two instances the enlarged nodes were surgically removed. Facing progressive osbtruction of both the airway and the esophagus, localized radiotheraphy (1800 cGy in nine fractions) to the right aspect of the neck was delivered with dramatic resolution of the node elargement; however, dissemination of the infection leading to a severe lung infiltration and respiratory failure ended the life of the patient
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Índice:
LILACS (Américas)
Assunto principal:
Pirazinamida
/
Radioterapia
/
Amicacina
/
Anticorpos Anti-HIV
/
Linfócitos T CD4-Positivos
/
Zidovudina
/
Ciprofloxacina
/
Western Blotting
/
Síndrome da Imunodeficiência Adquirida
/
Tuberculose Resistente a Múltiplos Medicamentos
Limite:
Adulto
/
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Arch. med. res
Assunto da revista:
Medicina
Ano de publicação:
1996
Tipo de documento:
Artigo
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