Identification of novel membrane structures in Plasmodium falciparum infected erythrocytes
Mem. Inst. Oswaldo Cruz
;
93(1): 115-20, Jan.-Feb. 1998. ilus
Artigo
em Inglês
| LILACS
| ID: lil-202005
RESUMO
Little is known about the molecular mechanisms underlying the release of merozoites from malaria infected erythrocytes. In this study membranous structures present in the culture medium at the time of merozoite release have been characterized. Biochemical and ultrastructural evidence indicate that membranous structures consist of the infected erythrocytes membrane, the parasitophorous vacuolar membrane and the residual body containing electron dense material. These are subcellular compartments expected in a structure that arises as a consequence of merozoite release from the infected cell. Ultrastrutural studies show that a novel structure extends from the former parasite compartment to the membrane. Since these membrane modifications are detected only after merozoites have been released from the infected erythrocyte, it is proposed that they might play a role in the release of merozoites from the host cell.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Plasmodium falciparum
/
Membrana Eritrocítica
/
Eritrócitos
Tipo de estudo:
Estudo diagnóstico
Limite:
Animais
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
1998
Tipo de documento:
Artigo
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