Cytokines in the modulation of eosinophilia
Mem. Inst. Oswaldo Cruz
;
92(supl.2): 109-14, Dec. 1997. tab, graf
Artigo
em Inglês
| LILACS
| ID: lil-202021
RESUMO
In this review we discuss our recently results showing interleukin 5 (IL-5) involvement in eosinophil migration and in the maintenance of eosinophilia in blood, bone marrow, lung and peritoneal cavity, in a visceral larva migrans syndrome model using guinea-pigs infected with Toxocara canis. We also describe the sequential release of TNF-a and IL-8 during the course of infection, and the interaction between these cytokines and IL-5 during infection. Finally, we propose a new biological role for IL-5, at least in our model, as a modulator of IL-8 release and secretion.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Citocinas
/
Toxocara canis
/
Eosinófilos
Tipo de estudo:
Estudo prognóstico
Limite:
Animais
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
1997
Tipo de documento:
Artigo
/
Congresso e conferência
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