Body-fundic gastric ulcer and helicobacter pylory: muco-peptic cells expnsion (immature cells) in helicobacter pylori positive patients
Acta gastroenterol. latinoam
;
27(5): 309-11, 1997. tab
Artigo
em Inglês
| LILACS
| ID: lil-205076
ABSTRACT
It is generally agreed that Helicobacter pylori (Hp) plays a key role in alterating regulatory factors affecting cellular proliferation during the disease process. During chronic superficial gastritis there is, in case of moderate/severe activity, a foveolar-superficial expansion of immature muco-peptic cells. In the present experience this phenomenon has been evaluated in the surrounding areas of 22 body-fundic gastric ulcer (BFGU). The 72.7 percent of BFGU were Hp positive. The expansion was detectable in 68.7 percent of Hp positive BFGU. The expansion process involves the substitution of mature cells with immature one determining a reduction of the efficacy of the mucosa barrier in association with an increment of aggresive factors (mucosal pepsins). This phenomenon in relation with host genetic susceptibility may favor peptic ulcer.
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Índice:
LILACS (Américas)
Assunto principal:
Úlcera Gástrica
/
Helicobacter pylori
/
Infecções por Helicobacter
/
Mucosa Gástrica
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Acta gastroenterol. latinoam
Assunto da revista:
Gastroenterologia
Ano de publicação:
1997
Tipo de documento:
Artigo
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