Inhibitory serum factor of lymphoproliferative response to allogeneic cells in pregnancy
São Paulo med. j
;
115(4): 1485-9, jul.-ago. 1997. tab, graf
Artigo
em Inglês
| LILACS
| ID: lil-208786
RESUMO
An inhibitory serum factor of mixed lymphocyte culture (MLC) has been associated with successful pregnancy after lymphocyte transfusion in women with unexplained recurrent spontaneous abortions (RSA). Objective: Investigate whether the inhibitory serum factor of MLC is essential for a successful pregnancy. Method: Sera from 33 healthy pregnant women and from 40 women with RSA were assessed by a one-way MLC in which the woman's lymphocytes were stimulated with her partner's lymphocytes or with third party lymphocytes. Results: An inhibitory serum effect (inhibition >50 percent as compared to normal serum) was detected in 45 percent of the pregnant women who had at least 1 previous parity, in 8 percent of the primigravidea, in 29 percent of those with one abortion and in 58 percent of those with more than one abortion. Conclusion: MLC inhibitory serum factor does not seem to be an essential factor for pregnancy development. Therefore, it should not be considered as a parameter for the assessment of RSA patients.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Sangue
/
Linfócitos
/
Aborto Habitual
/
Teste de Cultura Mista de Linfócitos
Limite:
Feminino
/
Humanos
/
Gravidez
Idioma:
Inglês
Revista:
São Paulo med. j
Assunto da revista:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Medicina
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Ano de publicação:
1997
Tipo de documento:
Artigo
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