The use of non-human primates as animal models for the study of hepatitis viruses
Braz. j. med. biol. res
;
31(8): 1035-48, Aug. 1998. tab
Artigo
em Inglês
| LILACS
| ID: lil-216826
ABSTRACT
Hepatitis viruses belong to different families and have in common a striking hepatotropsin and restrictions for propagation in cell culture. The transmissibility of hepatitis is in great part limited to non-human primates. Enterically transmitted hepatitis viruses (hepatitis A virus and hepatitis E virus) can induce hepatitis in a number of OLD World and New Worls monkey species, while the host range of non-human primates susceptible to hepatitis viruses transmitted by the parenteral route (hepatitis B virus, hepatitis C virus and hepatitis delta virus) is restricted to few species of Old World monkeys, especially the chimpanzee. Experimental studies on non-human primates have provided an invaluable source of information regarding the biology and pathogenesis of these viruses, and represent a still indispensable tool for vaccine and drug testing.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Cebidae
/
Cercopithecidae
/
Modelos Animais de Doenças
/
Hepatite Viral Animal
/
Vírus de Hepatite
Limite:
Animais
Idioma:
Inglês
Revista:
Braz. j. med. biol. res
Assunto da revista:
Biologia
/
Medicina
Ano de publicação:
1998
Tipo de documento:
Artigo
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