Nerve growth factor levels in normal human sera: study of the spontaneous motor activity in stumptailed monkeys

ABSTRACT

Nerve growth factor (NGF) is the best characterized of the neurotrophic factors, but there is incomplete information concerning its levels in body fluids. Normal values of NGF in serum from 157 normal subjets were determined by enzyme immunoassay (EIA). A mean NGF level of 194 ñ 25 pg ml-1 was obtained. There wee no statistically significant variations with age, but the NGF level was significantly lower in females (112 ñ 31 pg ml-1) than in males (243 ñ 35 pg ml-1)