Variations in white blood count, thromboxane B2 levels and hematocrit in chronic venous hypertension
São Paulo med. j
;
116(3): 1721-6, May-Jun. 1998. tab
Artigo
em Inglês
| LILACS
| ID: lil-224005
RESUMO
Objective:
To analyze variations in leukocyte count and thromboxane B2 production in the femoral vein of patients with chronic venous hypertension (CVH).Design:
Prospective clinical study, controlled, non randomized and open. Location Hospital das Cl[inicas, Faculdade de Medicina da Universidade de Sao Paulo, referral center, university hospital.Participants:
15 patients with recurring stasis ulcer were analyzed, selected randomly from the venous diseases outpatient center, and 4 without lower limb venous alterations were also analyzed. Intervention Blood samples from the femoral and brachial veins were drawn following supine and 45º reverse Trendelenburg. Main outcomesmeasures:
Direct leukocyte count and analysis of the thomboxane B2 with enzyme linked immunosorbent assay test.Results:
After 30 minutes in reverse Trendelenburg, patients with CVH showed a leukocyte count reduced by +27 per cent (p=0.02) and thromboxane B2 levels increased by +158 per cent (p=0.02).Conclusions:
We suggest that future studies of medications for stasis ulcers include their effects on leukocyte entrapment and thromboxane B2 production in the lower limb venous system.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Tromboxano B2
/
Úlcera Varicosa
/
Hematócrito
/
Contagem de Leucócitos
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo observacional
Limite:
Adolescente
/
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
São Paulo med. j
Assunto da revista:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Medicina
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Ano de publicação:
1998
Tipo de documento:
Artigo
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