Primary hyperparathyroidism due to parathyroid carcinoma
Arch. med. res
;
28(2): 303-6, jul. 1997. ilus, tab
Artigo
em Inglês
| LILACS
| ID: lil-225233
RESUMO
Most cases of primary hyperparathyroidism are due to either a parathyroid adenoma or to parathyroid hyperplasia. Parathyroid carcinoma is a very rare cause of hyperparathyroidism. Although the diagnosis of parathyroid carcinoma is usually established based on pathological criteria of vascular and capsular invasion, some clinical and biochemical features differentiate it from benign forms of hyperparathyroidism. We report the case of a middle-aged woman with a long standing history of nephrolithiasis, who presented with a palpable neck mass, wigh loss, severe hypercalcemia and hypophosphatemia, as well as very high serum levels of intact parathyroid hormone. Surgical neck exploration revealed a large tumor that invaded trache, esophagus, recurrent laryngeal nerve, right apical pleura and right carotid artery. Pathological examination confirmed the invasive nature of the tumor. Along with the case report, we review the literature and discuss the diagnostic and therapeutic options of this rare condition
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Índice:
LILACS (Américas)
Assunto principal:
Neoplasias das Paratireoides
/
Carcinoma
/
Hiperparatireoidismo
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Arch. med. res
Assunto da revista:
Medicina
Ano de publicação:
1997
Tipo de documento:
Artigo
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