Assessment of the functional capacity for intracellular dearth and phagocytosis of polymorphonuclear cells in healthy neonates
Arch. med. res
;
28(3): 401-6, sept. 1997. tab
Artigo
em Inglês
| LILACS
| ID: lil-225245
ABSTRACT
The objective of this study was to assess the functional capacity for intracellular death (ID) and/or phagocytic index (PI) of polymorphonuclear cells of 24-h-old healthy newborns with respect to the PMN cells of adults using the same standard exogenous source of opsonins. The ID and PI techniques were standardized and 2-3 ml of blood were used. No differences were found in the percentages of ID, P, PI among the PMNs of the newborns and those of the adults 43.95 ñ 15.70 vs. 44.56 ñ 8.43 for ID; 38.96 ñ 14.34 vs. 39.00 ñ 14.54 for P; 1.71 ñ 0.54 vs. 1.73 0.45 for PI, respectively. It was concluded that the PMNs of 24-h newborns have an ID, P, PI functionality comparable to adult PMNs; differences observed in PMN function in newborns may be due to humoral deficiencies (opsonins)
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Índice:
LILACS (Américas)
Assunto principal:
Fagocitose
/
Recém-Nascido
/
Citotoxicidade Imunológica
/
Neutrófilos
Limite:
Humanos
Idioma:
Inglês
Revista:
Arch. med. res
Assunto da revista:
Medicina
Ano de publicação:
1997
Tipo de documento:
Artigo
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