Alpha-Interferon therapy for HBV-related glomerulonephritis
São Paulo med. j
;
116(5): 1823-5, Sept.-Oct. 1998. graf
Artigo
em Inglês
| LILACS
| ID: lil-226004
ABSTRACT
We report a case of a patient with hepatitis B virus (HBV)-related membranous glomerulonephritis (MGN) who showed improvement after interferon-alpha (IFN-alpha) therapy. A 35-year-old man with nephrotic syndrome and HBV antigens received a 24-week course of IFN-alpha. At the end of therapy there was an elevation in the level of plasma aminotransferase and an increase in proteinuria, which were followed by antigen/antibody seroconversion. This "flare-up" before seroconversion suggests an increase in disease activity in the liver and kidney, demonstrating in vivo HBV involvement in MGN.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Antivirais
/
Glomerulonefrite Membranosa
/
Interferon-alfa
/
Hepatite B
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
São Paulo med. j
Assunto da revista:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Medicina
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Ano de publicação:
1998
Tipo de documento:
Artigo
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