HLA compatibility and graft survival in 502 kidney transplants

RESUMO

The survical of 502 kidney grafts (458 first-grafts and 44 seconda-grafts) performed at Hospital das Clínicas, Faculdade de Medicina, Universidade de Säo Paulo, was analyzed in relation to the degree of HLA compatibility. The actuarial graft survival for first-transplants, at 1 and 5 years, was a follows a) HLA-identical donor 90 and 83%; b) one-haplotype identical donor 68 and 54%; c) unrelated living donor 61 and 37.5% and d) cadaver donor 52.5 and 32%. These survival data are similar to those reported by other transplantation groups and confirm the important role of the HLA antigens in the outcome of renal transplantation