Effect of prenatal T4 treatment in neonatal morbidity: preliminary findings
P. R. health sci. j
;
16(1): 5-8, Mar. 1997.
Artigo
em Inglês
| LILACS
| ID: lil-228479
ABSTRACT
We report our experience with the use of intra-amniotic thyroxine to accelerate fetal maturation in preterm delivered infants. One hundred and fourteen infants who had received 500 micrograms of thyroxine weekly prenatally until an L/S ratio greater or equal to 2.0 was achieved, were compared to 113 premature infants who had not been given thyroxine or steroids prenatally. After stratification by weight, the relative incidence of respiratory distress syndrome (RDS), patent ductus arteriosus (PDA), necrotizing enterocolitis (NEC) and intraventricular hemorrhage (IVH) were compared. A decrease in the incidence of RDS was observed in the infants with birth weight between 1000 and 1500 g who had received more than one dose of intra-amniotic thyroxine. No difference in the incidence of RDS was observed in infants with birth weight of less than 1000 g or over 1500 g. One dose of thyroxine had no effect in decreasing the incidence of RDS, PDA, NEC, and IVH in any of the groups. We conclude intra-amniotic thyroxine seems to decreases the incidence of RDS in very low birth weight infants
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Índice:
LILACS (Américas)
Assunto principal:
Cuidado Pré-Natal
/
Síndrome do Desconforto Respiratório do Recém-Nascido
/
Tiroxina
/
Enterocolite Pseudomembranosa
/
Hemorragia Cerebral
/
Permeabilidade do Canal Arterial
Tipo de estudo:
Estudo diagnóstico
/
Estudo de incidência
/
Estudo prognóstico
Limite:
Feminino
/
Humanos
/
Recém-Nascido
/
Gravidez
Idioma:
Inglês
Revista:
P. R. health sci. j
Assunto da revista:
Medicina
Ano de publicação:
1997
Tipo de documento:
Artigo
País de afiliação:
Brasil
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