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Amyotropic lateral sclerosis with dementia: case report
Brito-Marques, Paulo Roberto; Mello, Roberto Vieira de.
Afiliação
  • Brito-Marques, Paulo Roberto; Universidade Federal de Pernambuco. Faculdade de Ciências Médicas. Departamento de Neurologia.
  • Mello, Roberto Vieira de; Potifícia Unversidade Católica de Campinas. Centro de Ciências Médicas. Departamento de Patologia.
Arq. neuropsiquiatr ; 57(2A): 277-83, jun. 1999. ilus
Article em En | LILACS | ID: lil-234463
Biblioteca responsável: BR1.1
RESUMO
A patients is described in whom a profound and rapidly progressive dementia occurred in association with clinical features of amyotrophic lateral sclerosis. A magnetic resonance imaging showed signs of frontal and especially left temporal atrophy. The pattern of dementia indicated impaired frontotemporal lobe functions, evidenced by reduced tracer uptake in the frontotemporal lobes on brain single photon emission computed tomography. Neuropathological examination in this patient revealed mild frontotemporal atrophy with spongiform changes and neuronal loss affecting mainly layers II and III of the frontotemporal cortices. There was atrophy of the hypoglossal nuclei. The spinal cord changes were consistent with motor neuron disease. The patient showed an irreversible and progressive course. A review of the relevant literature was made.
Assuntos
Texto completo: 1 Índice: LILACS Assunto principal: Demência / Esclerose Lateral Amiotrófica Limite: Aged / Female / Humans Idioma: En Revista: Arq. neuropsiquiatr Assunto da revista: NEUROLOGIA / PSIQUIATRIA Ano de publicação: 1999 Tipo de documento: Article
Texto completo: 1 Índice: LILACS Assunto principal: Demência / Esclerose Lateral Amiotrófica Limite: Aged / Female / Humans Idioma: En Revista: Arq. neuropsiquiatr Assunto da revista: NEUROLOGIA / PSIQUIATRIA Ano de publicação: 1999 Tipo de documento: Article