Percutaneous renal graft biopsy: a clinical, laboratory and pathological analysis
São Paulo med. j
;
117(2): 57-62, Mar. 1999. tab
Artigo
em Inglês
| LILACS
| ID: lil-240232
RESUMO
Renal allograft biopsies have been used as a good method for monitoring the evolution of kidney transplants for at least 20 years. Histological analysis permits differential diagnosis of the causes of allograft dysfunction to be made. Objectives:
To correlate the data of urinalysis and serum creatinine with histological diagnosis of renal graft in a group of renal transplant patients.Design:
Accuracy study, retrospective analysis.Setting:
A university terciary referral center. Sample 339 percutaneous allograft biopsies obtained from 153 patients. Blood and urine samples were obtained before the graft biopsy. Main Measurements Laboratory evolution and hystological analysis (light microscopy, imunofluorescent eletronic microscopy).Results:
Most of the biopsies (58.9 per cent) were performed during the first month post-transplant. An increase in serum creatinine was associated with acute tubular and/or cortical necrosis. Proteinuria and normal serum creatinine were associated with glomerular lesions. Non-nephrotic range proteinuria and an increase in serum creatinine were associated with chronic rejection.Conclusion:
Evaluation of serum creatinine and urinalysis can be useful in suggesting the histological graft diagnosis.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Biópsia por Agulha
/
Transplante de Rim
/
Rejeição de Enxerto
/
Rim
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
/
Fatores de risco
Limite:
Humanos
Idioma:
Inglês
Revista:
São Paulo med. j
Assunto da revista:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Medicina
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Ano de publicação:
1999
Tipo de documento:
Artigo
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