Olive oil protects against chromosomal aberrations induced by doxorubicin in wistar rat bone marrow cells
Genet. mol. biol
;
22(2): 225-7, jun. 1999. tab
Artigo
em Inglês
| LILACS
| ID: lil-242205
RESUMO
There is considerable interest in identifying dietary compounds which have the capacity to protect against chromosomal aberrations induced by antitumor agents. Fatty acids and their constituents are able to act as free radical scavengers. Doxorubicin (DXR) is an important chemotherapeutic agent, that also induces chromosome aberrations. Rat bone marrow cells treated simultaneously with olive oil (10 ml/kg body weight) and DXR (90 mg/kg body weight) developed significantly fewer chromosomal aberrations and abnormal metaphases than those treated with DXR alone.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Óleos de Plantas
/
Células da Medula Óssea
/
Doxorrubicina
/
Aberrações Cromossômicas
/
Antineoplásicos
Limite:
Animais
Idioma:
Inglês
Revista:
Genet. mol. biol
Assunto da revista:
Genética
Ano de publicação:
1999
Tipo de documento:
Artigo
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