In vitro evaluation of erythromycin in chloroquine resistant brazilian P. falciparum freshly isolates: modulating effect and antimalarial activity evidence
Rev. Inst. Med. Trop. Säo Paulo
;
41(4): 249-53, July-Aug. 1999.
Artigo
em Inglês
| LILACS, SES-SP
| ID: lil-246835
ABSTRACT
Erythromycin, a reversal agent in multidrug-resistant cancer, was assayed in chloroquine resistance modulation. The in vitro microtechnique for drug susceptibility was employed using two freshly isolates of Plasmodium falciparum from North of Brazil. The antimalarial effect of the drug was confirmed, with an IC50 estimates near the usual antimicrobial therapy concentration, and a significant statistical modulating action was observed for one isolate
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Plasmodium falciparum
/
Técnicas In Vitro
/
Cloroquina
/
Eritromicina
/
Resistência a Múltiplos Medicamentos
/
Antimaláricos
Limite:
Animais
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Rev. Inst. Med. Trop. Säo Paulo
Ano de publicação:
1999
Tipo de documento:
Artigo
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