Drug resitance of yeasts isolated from oropharyngeal candidiasis in AIDS patients
Rev. microbiol
;
29(4): 272-5, out.-dez. 1998. tab, graf
Artigo
em Inglês
| LILACS
| ID: lil-251735
ABSTRACT
"Candida spp" was isolated from 59 (68.60 (per cent)) out of eighty six samples of oral mucosa of AIDS patients. The identification, based or the production of a germ tube and chlamydospores, and on the assimilation and fermentation of carbohydrates, revealed 52 strains (88.13 (per cent)) of "C. albicans", 4 (6.77 (per cent)) od "C. tropicalis" and 3 (5.08 (per cent)) of "C. krusei". The susceptibility of these strains to amophotericin B, flucytosine, itraconazole, fluconazole and ketoconazole was determined using the agar dilution method. Comparing the minimum inhibitory concentration values found in the susceptibility test with the serum levels achieved by these drugs, only 8.47 (per cent) and 5.08 (per cent) of the yeast strains proved to be resistant to amphotericin B and flucitosyne, repsctively. A high frequency of strains resistant to azole derivates (25.42 (per cent) to intraconazole, 45.76 (per cent), to ketoconazole and 66.10 (per cent) to fluconazole) was observed.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Orofaringe
/
Técnicas In Vitro
/
Candida
/
Candidíase
/
Síndrome da Imunodeficiência Adquirida
/
Infecções Oportunistas Relacionadas com a AIDS
/
Antifúngicos
Limite:
Humanos
Idioma:
Inglês
Revista:
Rev. microbiol
Assunto da revista:
Microbiologia
Ano de publicação:
1998
Tipo de documento:
Artigo
País de afiliação:
Brasil
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