Glomerulonefritis crescéntica con anticuerpos anticitoplasma de neutrófilos (+) en niños: casos clínicos / Anti neutrophil cytoplasmic antibody positive crescentic glomerulonephritis in children: report of 2 cases

ABSTRACT

Anti neutrophil cytoplasmic antibodies are associated to vasculitis and crescentic glomerulonephritis in adults. However, this association has been seldom reported in children. We report two girls aged 12 and 15 years old with ANCA + glomerulonephritis. Both were subjected to a percutaneous kidney biopsy. One girl had to enter a chronic hemodialysis program. The other patient recovered her renal function and after 12 months of treatment with steroids and cyclophosphamide microscopic hematuria and proteinuria persist but with normal kidney function. ANCA should be measured in children with vasculitis and glomerulonephritis