Neurocysticercosis: detection of IgG, IgA and IgE antibodies in cerebrospinal fluid, serum and saliva samples by ELISA with Taenia solium and Taenia crassiceps antigens
Arq. neuropsiquiatr
;
58(1): 18-24, mar. 2000. tab, ilus
Artigo
em Inglês
| LILACS
| ID: lil-255059
ABSTRACT
We assayed samples of cerebrospinal fluid (CSF), serum and saliva from patients with neurocysticercoses, control group and individuals with other parasitoses, by ELISA with Taenia crassiceps vesicular fluid antigen (Tcra) and Taenia solium total antigen (Tso) for the detection of antibodies. The sensitivity for IgG-Tcra was 100 per cent for CSF and serum, and 32.0 per cent for saliva; and for IgG-Tso 100 per cent for CSF, 80.0 per cent for serum and 24 per cent for saliva. Specificity was 100 per cent for CSF and 80.0 per cent for serum with both antigens, and 100 per cent for saliva with Tcra and 87.5 per cent with Tso. The sensitivity and specificity for IgA-Tcra was, respectively, 40.0 per cent and 100 per cent for CSF, 36.0 per cent and 97.1 per cent for serum, and 4.0 per cent and 90.0 per cent for saliva. IgE detection showed 24.0 per cent sensitivity and 97.1 per cent specificity for serum, with no detection in CSF samples. The search for antibodies revealed the presence of IgG > IgA > IgE in CSF, serum and saliva samples, with IgG being present in all phases of the disease, while IgA/IgE were more frequent in the inactive form.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Taenia
/
Isotipos de Imunoglobulinas
/
Neurocisticercose
/
Antígenos de Helmintos
Tipo de estudo:
Estudo diagnóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
Arq. neuropsiquiatr
Assunto da revista:
Neurologia
/
Psiquiatria
Ano de publicação:
2000
Tipo de documento:
Artigo
País de afiliação:
Brasil
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