Further studies on vertebrate S-type lectins: cross-reactivity between toad and human lectins
Biol. Res
;
30(3): 99-104, 1997. ilus, tab
Artigo
em Inglês
| LILACS
| ID: lil-255651
ABSTRACT
Galectins (S-type or S-Lac lectins) are a well-defined family of beta-galactoside animal lectins characterized by a high sequence homology in the carbohydrate-binding domain. We have previously purified and characterized the S-type lectin from the ovary of the toad Bufo arenarum. In this study, we purified the S-type lectins from Bufo arenarum ovary and human spleen by an improved method which included ion exchange and affinity chromatography. Antibody cross-reactivities between both lectins and some other S-type lectins showed that they share epitopes. Glycosylation studies carried out with detection/differentiation kits suggested that both lectins are not glycosylated
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Índice:
LILACS (Américas)
Assunto principal:
Lectinas
Limite:
Animais
/
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Biol. Res
Assunto da revista:
Biologia
Ano de publicação:
1997
Tipo de documento:
Artigo
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