Study of Schistosoma mansoni isolates from patients with failure of treatment with oxamniquine
Mem. Inst. Oswaldo Cruz
;
95(3): 375-80, May-Jun. 2000. tab
Artigo
em Inglês
| LILACS
| ID: lil-258192
ABSTRACT
After three successive treatments with oxamniquine the continuing elimination of Schistosoma mansoni eggs was observed in patients, who came from various regions of Brazil, with different clinical forms of schistosomiasis. The objective of the present study was to determine the experimental behaviour of five different S. mansoni isolates in Swiss Webster mice that were submitted to treatment with the same drug. The experimental group with failure of treatment showed higher mean number of surviving male worms when it was compared to the group without failure of treatment. These date suggest the possibility of resistance to oxamniquine.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Oxamniquine
/
Schistosoma mansoni
/
Esquistossomicidas
/
Esquistossomose mansoni
Limite:
Animais
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
2000
Tipo de documento:
Artigo
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