Inmunosenescencia: pruebas cutáneas de hipersensibilidad retardada en adultos mayores chilenos autovalentes / Immunosenescence: delayed cutaneous hypersensitivity test in free living chilean elderly individuals
Rev. méd. Chile
;
128(4): 379-86, abr. 2000. tab
Artigo
em Espanhol
| LILACS
| ID: lil-263706
ABSTRACT
Background:
Delayed cutaneous hypersensitivity tests are a globally accepted test to assess cellular immunity in vivo. The quality and quantity of the response to these type of tests, varies in different populations.Aim:
To study delayed cutaneous hypersensitivity in a group of healthy Chilean elders. Material andmethods:
Forty two elders (32 male), aged 60 to 76 years old were studied. Multitest-CMI(r) was applied in the left forearm. This test allows the subcutaneous administration of seven antigens and a glycerin control. Results were compared with those of a group of young adults studied by the authors.Results:
Among males there was a mean of 2.7 ñ 1.4 positive responses compared with women, that had 1.7 ñ 1 positive responses (p= 0.016). The sum of response diameters was 4.2 ñ 1.5 and 3.6 ñ 1.9 mm in men and women respectively (p = NS). Compared to young adults, elderly women had a lower response to tetanus and diphtheria toxoids and men had a lower response to diphtheria and Proteus mirabilis.Conclusions:
Elderly people have a less intense response to delayed cutaneous hypersensitivity tests than young adults. This response must be assessed in each population to account for regional variability
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Testes Imunológicos
Tipo de estudo:
Estudo diagnóstico
Limite:
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
América do Sul
/
Chile
Idioma:
Espanhol
Revista:
Rev. méd. Chile
Assunto da revista:
Medicina
Ano de publicação:
2000
Tipo de documento:
Artigo
País de afiliação:
Chile
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