Hepatite aguda colestática pelo propiltiouracil. Relato de caso / Acute cholestatic hepatitis induced by propylthiouracil. case report
Arq. gastroenterol
;
37(2): 129-32, abr.-jun. 2000. ilus
Artigo
em Português
| LILACS
| ID: lil-279428
ABSTRACT
Propylthiouracil is widely used to treat patients with hyperthyroidism. However, propylthiouracil-induced hepatitis is an uncommon entity. The case of a 15-year-old boy treated with propylthiouracil for hyperthyroidism who developed a cholestatic acute hepatitis is reported. Viral, metabolic and autoimmune liver diseases were excluded and liver biopsy showed a pattern suggestive of drug-induced cholestatic hepatitis. After discontinuing the drug, there was a progressive resolution of symptoms and normalization of liver biochemical tests. Despite its rarity, patients receiving propylthiouracil are exposed to develop severe hepatotoxicity
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Propiltiouracila
/
Antitireóideos
/
Colestase Intra-Hepática
/
Doença Hepática Induzida por Substâncias e Drogas
Limite:
Adolescente
/
Humanos
/
Masculino
Idioma:
Português
Revista:
Arq. gastroenterol
Assunto da revista:
Gastroenterologia
Ano de publicação:
2000
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade Federal do Paraná/BR
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