Population genetic analysis of Colombian Trypanosoma cruzi isolates revealed by enzyme electrophoretic profiles
Mem. Inst. Oswaldo Cruz
;
96(1): 31-51, Jan. 2001. ilus, tab
Artigo
em Inglês
| LILACS
| ID: lil-281629
RESUMO
Although Colombia presents an enormous biological diversity, few studies have been conducted on the population genetics of Trypanosoma cruzi. This study was carried out with 23 Colombian stocks of this protozoa analyzed for 13 isoenzymatic loci. The Hardy-Weinberg equilibrium, the genetic diversity and heterogeneity, the genetic relationships and the possible spatial structure of these 23 Colombian stocks of T. cruzi were estimated. The majority of results obtained are in agreement with a clonal population structure. Nevertheless, two aspects expected in a clonal structure were not discovered in the Colombian T. cruzi stocks. There was an absence of given zymodemes over-represented from a geographical point of view and the presumed temporal stabilizing selective phenomena was not observed either in the Colombian stocks sampled several times through the years of the study. Some hypotheses are discussed in order to explain the results found
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Comportamento Espacial
/
Trypanosoma cruzi
/
Enzimas
/
Genética Populacional
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
América do Sul
/
Colômbia
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
2001
Tipo de documento:
Artigo
País de afiliação:
Bolívia
/
Colômbia
Instituição/País de afiliação:
Instituto Nacional de Salud/CO
/
Pontifica Universidad Javerina/CO
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