Células natural killer y el sistema inmune innato en la patología infecciosa / Natural killer cells and the innate immune system in infectious diseases
Rev. méd. Chile
;
128(12): 1361-70, dic. 2000. ilus, tab
Artigo
em Espanhol
| LILACS
| ID: lil-281996
RESUMO
Natural killer (NK) cells form a unique third group of lymphocytes that differs from T and B cells in surface phenotype, target cell recognition and function. NK cells have two relevant functions, related to the innate immune response against pathogens microorganisms. One is cytotoxicity, mediated by the recognition and lysis of target cells such as virus and bacteria infected-cells. The second NK cell function is to produce cytokines, mainly IFN-g, that can modulate innate and specific immune responses. Cytotoxicity and cytokine secretion contribute to host resistance against microorganisms and both functions are significantly altered in infectious diseases
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Células Matadoras Naturais
/
Doenças Transmissíveis
/
Subpopulações de Linfócitos
Limite:
Humanos
Idioma:
Espanhol
Revista:
Rev. méd. Chile
Assunto da revista:
Medicina
Ano de publicação:
2000
Tipo de documento:
Artigo
/
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