Anesthesia of Biomphalaria spp. (Mollusca, Gastropoda): sodium pentobarbital is the drug of choice
Mem. Inst. Oswaldo Cruz
;
96(3): 391-392, Apr. 2001. tab
Artigo
em Inglês
| LILACS
| ID: lil-282851
ABSTRACT
The anesthetic effect of some water-soluble anesthesic or narcotic drugs currently used in mice was tested in molluscs of the Biomphalaria genus. Sodium thiopental was very toxic to the snails resulting in high rates of mortality in all the treatment schedules tested. Cetamine base, at concentration of 0.25 mg/ml of water, resulted in partial snail anesthesia (40 percent of snails were anesthetized) only after 20 h of exposition. The association of Cetamine base with Tiazine chloridrate did not improve the anesthesic effect, and higher concentrations of these drugs were toxic to the snails. Sodium pentobarbital at 0.4 mg/ml in water for 8 h was the best treatment schedule to anesthetize Biomphalaria snails. In this schedule, the snails were anesthetized without any toxic effect. The procedure provides a powerful tool for in vivo studies that demande a complete state of snail anesthesia
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Pentobarbital
/
Biomphalaria
/
Adjuvantes Anestésicos
Limite:
Animais
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
2001
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Santa Casa de Misericórdia/BR
/
Universidade Federal de Minas Gerais/BR
/
Universidade Federal do Ceará/BR
Similares
MEDLINE
...
LILACS
LIS