Effects of milk from goat fed Crotalaria spectabilis seeds on growing rats
Braz. j. vet. res. anim. sci
;
36(2): 97-100, 1999. ilus, tab
Artigo
em Inglês
| LILACS
| ID: lil-283497
ABSTRACT
Seeds of Crotalaria spectabilis, containing the pyrrolizidine alkaloid (PA) monocrotaline (MCT), were fed to a lactating dairy goat. Milk from this goat was fed to rats for 8 weeks to determine whether MCT or its toxic metabolites are transferred into the goat's milk. Rats from the experimental group showed significantly higher (p<0.05) serum levels of ALT, AST, GGT and LDH and less weight gains (p<0.05) than control rats. The most significant lesions in rats consuming the experimental ration were mild to moderate interstitial pneumonia and a vacuolar degeneration and occasionally necrosis of periportal hepatocytes. The results of this study indicate that the PA and/or its metabolites are eliminated in milk
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Intoxicação
/
Alcaloides de Pirrolizidina
/
Leite
Limite:
Animais
Idioma:
Inglês
Revista:
Braz. j. vet. res. anim. sci
Assunto da revista:
Medicina Veterinária
Ano de publicação:
1999
Tipo de documento:
Artigo
País de afiliação:
Brasil
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