Replacing oxamniquine by praziquantel against Schistosoma mansoni infection in a rural community from the sugar-cane zone of Northeast Brazil: an epidemiological follow-up
Mem. Inst. Oswaldo Cruz
;
96(suppl): 165-167, Sept. 2001. graf
Artigo
em Inglês
| LILACS
| ID: lil-295888
ABSTRACT
A group of 52 villagers was followed-up for three years regarding Schistosoma mansoni infection. All villagers were periodically surveyed by the Kato-Katz method. In March 1997 and March 1998 the positives were treated with oxamniquine (15-20 mg/kg), and in March 1999, with praziquantel (60 mg/kg). All infection indices decreased substantially between March 1999 and March 2000 prevalence of infection (from 32.7 percent to 21.2 percent), prevalence of moderate/heavy infection (from 7.7 percent to 1.9 percent), intensity of infection (from 23.1 epg to 7.4 epg) and reinfection (from 35.7 percent to 14.3 percent). Negativation increased from 53.8 to 82.4. An optimistic prognostic is assumed in the short term for the introduction of praziquantel in the study area
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Oxamniquine
/
Praziquantel
/
Esquistossomicidas
/
Esquistossomose mansoni
/
Anti-Helmínticos
Tipo de estudo:
Estudo observacional
/
Estudo de prevalência
/
Estudo prognóstico
/
Fatores de risco
Limite:
Animais
/
Humanos
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
2001
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Fiocruz/BR
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