Arterial distensibility as a possible compensatory mechanism in chronic aortic regurgitation
Arq. bras. cardiol
;
77(3): 262-265, Sept. 2001. ilus, tab
Artigo
em Inglês
| LILACS
| ID: lil-298657
RESUMO
OBJECTIVE:
To evaluate elastic properties of conduit arteries in asymptomatic patients who have severe chronic aortic regurgitation.METHODS:
Twelve healthy volunteers aged 30Ý1 years (control group) and 14 asymptomatic patients with severe aortic regurgitation aged 29Ý2 years and left ventricular ejection fraction of 0.61Ý0.02 (radioisotope ventriculography) were studied. High-resolution ultrasonography was performed to measure the systolic and diastolic diameters of the common carotid artery. Simultaneous measurement of blood pressure enabled the calculation of arterial compliance and distensibility.RESULTS:
No differences were observed between patients with aortic regurgitation and the control group concerning age, sex, body surface, and mean blood pressure. Pulse pressure was significantly higher in the aortic regurgitation group compared with that in the control group (78Ý3 versus 48Ý1mmHg, P<0.01). Arterial compliance and distensibility were significantly greater in the aortic regurgitation group compared with that in the control group (11.0Ý0.8 versus 8.1Ý0.7 10-10 N-1 m4, P=0.01 e and 39.3Ý2.6 versus 31.1Ý2.0 10-6 N-1 m², P=0.02, respectively).CONCLUSION:
Patients with chronic aortic regurgitation have increased arterial distensibility. Greater vascular compliance, to lessen the impact of systolic volume ejected into conduit arteries, represents a compensatory mechanism in left ventricular and arterial system coupling
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Insuficiência da Valva Aórtica
/
Artérias
/
Função Ventricular Esquerda
Tipo de estudo:
Estudo observacional
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Arq. bras. cardiol
Assunto da revista:
Cardiologia
Ano de publicação:
2001
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
University of Säo Paulo/BR
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