Worm load and septal fibrosis of the liver in Capillaria hepatica-infected rats
Mem. Inst. Oswaldo Cruz
;
96(7): 1001-1003, Oct. 2001. ilus
Artigo
em Inglês
| LILACS
| ID: lil-298898
ABSTRACT
Inocula, varying from 15 to 1,000 embryonated Capillaria hepatica eggs, were administered to young adult rats by gastric tube, in an attempt to investigate the influence of worm load in the production of septal fibrosis of the liver. Low doses of 15, 30 or 50 eggs were sufficient to produce septal fibrosis, but it appeared with variable degrees of intensity and always with focal distribution. Septal fibrosis became diffuse, progressive with time, and already well developed 40 days after infection, when 100 eggs or more were administered. However, higher inocula (200, 500 and 1,000 eggs) did not intensify septal fibrosis, although the number of parasitic focal lesions proportionally augmented
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Capillaria
/
Infecções por Enoplida
/
Cirrose Hepática Experimental
/
Hepatopatias Parasitárias
Tipo de estudo:
Estudo prognóstico
Limite:
Animais
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
2001
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Fiocruz/BR
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