Alcohol induced liver disease: from molecular damage to treatment
Rev. méd. Chile
;
130(6): 681-690, jun. 2002. tab, graf
Artigo
em Inglês
| LILACS
| ID: lil-317502
ABSTRACT
Although the interaction between alcohol and the liver has been the subject of intensive investigation since many years, several uncertainties remain to be solved. Good examples of what we need to learn are The real number of patients with alcohol-induced liver disease (AILD), the dose of alcohol "safe" for the liver, the genetic predisposition to the damage or, on the other side of the coin, protecting from the damage. Rather recently, however, part of these questions started to be clarified, thus permitting a better definition of the role of each of these factors in AILD. In parallel to the clinical approach to AILD, the unveiling of the molecular and biochemical mechanisms involved in AILD has progressed and proved to be important in both a better understanding of the disease and, more important, in a more rational treatment of these disorders. This review will focus on what we currently know of AILD in clinical, biochemical and molecular terms and what we need to address in the future
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Etanol
/
Hepatopatias Alcoólicas
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Rev. méd. Chile
Assunto da revista:
Medicina
Ano de publicação:
2002
Tipo de documento:
Artigo
/
Documento de projeto
País de afiliação:
Itália
/
Espanha
Instituição/País de afiliação:
Fondo Studio Malattie de Fegato/IT
/
Hospital Clinic i Provincial/ES
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