Reactividad de sueros de pacientes chagásicos crónicos con extractos de aislamientos mexicanos de Trypanosoma cruzi / Reactivity of sera from Chagas patients to extracts of mexican Trypanosoma cruzi isolates
Rev. biol. trop
;
41(3B): 861-865, Dic. 1993.
Artigo
em Espanhol
| LILACS
| ID: lil-320072
ABSTRACT
An antigenic extract prepared from four different Mexican isolates of Trypanosoma cruzi cultured on BHI (three came from human cases-Agripina, Fidelfa and Ninoa, and other from triatoma-Cocula) were assayed with human sera. ELISA results always were consistent with clinical diagnosis. Sera from patients with a diagnosis of Chagas disease were reactive and non-chagasic sera were negative. Western blot of chagasic sera recognized antigens of molecular weight > 81 kd, 81 kd, 54 kd, 42 kd, and 26 kd. Sera with high OD in ELISA reacted with more peptide bands. The soluble extract antigens prepared from Mexican isolates of T. cruzi and from the Brazilian Y strain have an homogenous and similar reactivity.
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Índice:
LILACS (Américas)
Assunto principal:
Extratos de Tecidos
/
Trypanosoma cruzi
/
Doença de Chagas
Tipo de estudo:
Estudo diagnóstico
Limite:
Animais
/
Humanos
País/Região como assunto:
México
Idioma:
Espanhol
Revista:
Rev. biol. trop
Assunto da revista:
Biologia
/
Medicina Tropical
Ano de publicação:
1993
Tipo de documento:
Artigo
País de afiliação:
México
Instituição/País de afiliação:
Instituto Nacional de Cardiología I Chávez/MX
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