Comparative study on the localization of adult Schistosoma mansoni worms in albino mice anesthetized with pentobarbital sodium, ether or chloroform
Rev. Inst. Med. Trop. Säo Paulo
;
35(4): 323-326, Jul.-Aug. 1993.
Artigo
em Inglês
| LILACS
| ID: lil-320562
ABSTRACT
The effect of anesthetic drugs on the localization of adult worms in albino mice was compared. The animals with 56 days of infection were anesthetized with pentobarbital sodium, ether or chloroform. Perfusion was carried out immediately after, recovering the worms and classifying them in relation to their localization on the liver or portal vein and the mesenteric veins. Our results showed that pentobarbital sodium produced a greater displacement of the worms to the liver (89) than ether (76) and chloroform (34) did, when compared to the control group (22). The difference between pentobarbital sodium and ether was significant (p < 0.05). We suggest that anesthetic drugs may not be used in studies on the distribution of adult worms in several hosts.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Pentobarbital
/
Schistosoma mansoni
/
Clorofórmio
/
Éter
Limite:
Animais
Idioma:
Inglês
Revista:
Rev. Inst. Med. Trop. Säo Paulo
Assunto da revista:
Medicina Tropical
Ano de publicação:
1993
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Institute Oswaldo Cruz Foundation/BR
/
National Insitute of Helath Quality and Control/BR
/
UERJ/BR
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