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Comparative study on the localization of adult Schistosoma mansoni worms in albino mice anesthetized with pentobarbital sodium, ether or chloroform
Machado e Silva, José Roberto; Lima, Maria Adriana Dias de; Rodrigues e Silva, Rosangela; Maldonado Júnior, Arnaldo; Presgrave, Octavio Augusto F; Rey, Luis.
  • Machado e Silva, José Roberto; UERJ. Department of Pathology and Laboratory Services. BR
  • Lima, Maria Adriana Dias de; Institute Oswaldo Cruz Foundation. Department of Tropical Medicine. Rio de Janeiro. BR
  • Rodrigues e Silva, Rosangela; Institute Oswaldo Cruz Foundation. Department of Tropical Medicine. Rio de Janeiro. BR
  • Maldonado Júnior, Arnaldo; Institute Oswaldo Cruz Foundation. Department of Tropical Medicine. Rio de Janeiro. BR
  • Presgrave, Octavio Augusto F; National Insitute of Helath Quality and Control. BR
  • Rey, Luis; Institute Oswaldo Cruz Foundation. Department of Tropical Medicine. Rio de Janeiro. BR
Rev. Inst. Med. Trop. Säo Paulo ; 35(4): 323-326, Jul.-Aug. 1993.
Artigo em Inglês | LILACS | ID: lil-320562
ABSTRACT
The effect of anesthetic drugs on the localization of adult worms in albino mice was compared. The animals with 56 days of infection were anesthetized with pentobarbital sodium, ether or chloroform. Perfusion was carried out immediately after, recovering the worms and classifying them in relation to their localization on the liver or portal vein and the mesenteric veins. Our results showed that pentobarbital sodium produced a greater displacement of the worms to the liver (89) than ether (76) and chloroform (34) did, when compared to the control group (22). The difference between pentobarbital sodium and ether was significant (p < 0.05). We suggest that anesthetic drugs may not be used in studies on the distribution of adult worms in several hosts.
Assuntos
Texto completo: DisponíveL Índice: LILACS (Américas) Assunto principal: Pentobarbital / Schistosoma mansoni / Clorofórmio / Éter Limite: Animais Idioma: Inglês Revista: Rev. Inst. Med. Trop. Säo Paulo Assunto da revista: Medicina Tropical Ano de publicação: 1993 Tipo de documento: Artigo País de afiliação: Brasil Instituição/País de afiliação: Institute Oswaldo Cruz Foundation/BR / National Insitute of Helath Quality and Control/BR / UERJ/BR

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Texto completo: DisponíveL Índice: LILACS (Américas) Assunto principal: Pentobarbital / Schistosoma mansoni / Clorofórmio / Éter Limite: Animais Idioma: Inglês Revista: Rev. Inst. Med. Trop. Säo Paulo Assunto da revista: Medicina Tropical Ano de publicação: 1993 Tipo de documento: Artigo País de afiliação: Brasil Instituição/País de afiliação: Institute Oswaldo Cruz Foundation/BR / National Insitute of Helath Quality and Control/BR / UERJ/BR