New prevalence estimate of TT virus (TTV) infection in low- and high-risk population from Säo Paulo, Brazil
Rev. Inst. Med. Trop. Säo Paulo
;
44(4): 233-234, July-Aug. 2002. tab
Artigo
em Inglês
| LILACS, SES-SP
| ID: lil-321227
ABSTRACT
The prevalence of TT virus (TTV) infection was investigated by Polymerase Chain Reaction (PCR) in low- (blood donors and healthy children/adolescents) and high-risk (hemophiliacs) groups from Säo Paulo, Brazil. Primers based on the untranslated region (UTR) of the viral genome proved to be much more ubiquitous, leading to much higher frequencies for both groups ( > or = 81 percent) than the earlier N22-PCR directed to the open reading frame 1 (blood donors, 5.5 percent, and hemophiliacs, 42.3 percent). The UTR-PCR also revealed an interesting profile for healthy children/adolescents very high prevalence at the early years and significant decrease in male teenagers. The N22-PCR, in turn, demonstrated higher frequency in hemophiliacs treated with fresh blood products (58 percent), than in those treated with virus-inactivated clotting factors (9.4 percent) and blood donors (5.5 percent)
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Torque teno virus
/
Infecções por Vírus de DNA
Tipo de estudo:
Estudo de etiologia
/
Estudo de prevalência
/
Fatores de risco
Limite:
Adolescente
/
Criança
/
Criança, pré-escolar
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Rev. Inst. Med. Trop. Säo Paulo
Ano de publicação:
2002
Tipo de documento:
Artigo
Instituição/País de afiliação:
Fundaçäo Pró-Sangue Hemocentro de São Paulo/BR
/
Fundaçäo Pró-Sangue Hemocentro de Säo Paulo/BR
/
Institute of Infectology "Emílio Ribas"/BR
/
University of Säo Paulo/BR
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