Parasitological characteristics of Schistosoma mansoni infection in swiss mice with underlying malnutrition
Mem. Inst. Oswaldo Cruz
;
97(suppl.1): 143-147, Oct. 2002. graf
Artigo
em Inglês
| LILACS
| ID: lil-325019
ABSTRACT
The effects of a protein-restricted diet (8 percent protein, 81 percent carbohydrate and 11 percent lipids) on Schistosoma mansoni infectivity, fecal egg excretion and intestinal egg distribution in Swiss (SW) mice were studied. Pregnant mice received a deficient diet from the middle of gestation until delivery. Seven-days-old mice were exposed to 50 cercariae (BH strain, Brazil). Offspring mice had a free access to the deficient diet since lactation until adulthood. The controls were fed with a commercial mice diet. A parasitological examination was performed between six and eight weeks post-infection while both groups were necropsied one week later. Mice on the experimental diet showed a significant loss in body weight. There was no significant difference (p > 0.05) in pre-patent period, kinetics of egg excretion and worm recovery from mice on either diet. Significant differences (p < 0.05) were found concerning to the percentage of deposited eggs in the distal segment of the small intestine from hosts on the experimental diet.Our data suggest that experimental malnutrition induced for a long term has no detrimental effect on the acute schistosomiais infection in SW mice
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Schistosoma mansoni
/
Esquistossomose mansoni
/
Proteínas Alimentares
/
Desnutrição Proteico-Calórica
Tipo de estudo:
Estudo prognóstico
Limite:
Animais
/
Gravidez
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
2002
Tipo de documento:
Artigo
/
Congresso e conferência
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade do Estado do Rio de Janeiro/BR
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