Pathogenesis of Salmonella-induced enteritis
Braz. j. med. biol. res
;
36(1): 03-12, Jan. 2003. ilus, tab
Artigo
em Inglês
| LILACS
| ID: lil-326306
ABSTRACT
Infections with Salmonella serotypes are a major cause of food-borne diseases worldwide. Animal models other than the mouse have been employed for the study of nontyphoidal Salmonella infections because the murine model is not suitable for the study of Salmonella-induced diarrhea. The microbe has developed mechanisms to exploit the host cell machinery to its own purpose. Bacterial proteins delivered directly into the host cell cytosol cause cytoskeletal changes and interfere with host cell signaling pathways, which ultimately enhance disease manifestation. Recently, marked advances have been made in our understanding of the molecular interactions between Salmonella serotypes and their hosts. Here, we discuss the molecular basis of the pathogenesis of Salmonella-induced enteritis
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Salmonelose Animal
/
Salmonella typhimurium
/
Diarreia
/
Enterite
Tipo de estudo:
Estudo de etiologia
/
Estudo prognóstico
Limite:
Animais
Idioma:
Inglês
Revista:
Braz. j. med. biol. res
Assunto da revista:
Biologia
/
Medicina
Ano de publicação:
2003
Tipo de documento:
Artigo
/
Documento de projeto
País de afiliação:
Brasil
/
Estados Unidos
Instituição/País de afiliação:
Texas A&M University System/US
/
Texas A&M University/US
/
Universidade Federal de Minas Gerais/BR
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