A novel reiterated family of transcribed oligo(A)-terminated, interspersed DNA elements in the genome of Trypanosoma cruzi
Mem. Inst. Oswaldo Cruz
;
98(1): 129-133, Jan. 30, 2003. ilus
Artigo
em Inglês
| LILACS
| ID: lil-331390
ABSTRACT
We report the molecular characterization of a novel reiterated family of transcribed oligo(A)-terminated, interspersed DNA elements in the genome of Trypanosoma cruzi. Steady-state level of transcripts of this sequence family appeared to be developmentally regulated, since only in the replicative forms the parasite showed expression of related sequences with a major band around 3 kb. The presence of frame shifts or premature stop codons predicts that transcripts are not translated. The sequence family also contains truncated forms of retrotransposons elements that may become potential hot spots for retroelement insertion. Sequences homologous to this family are interspersed at many chromosomes including the subtelomeric regions
Texto completo:
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Índice:
LILACS (Américas)
Assunto principal:
Trypanosoma cruzi
/
DNA de Protozoário
/
Genoma de Protozoário
/
Sequências Repetitivas Dispersas
Limite:
Animais
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
2003
Tipo de documento:
Artigo
/
Documento de projeto
País de afiliação:
Brasil
/
Chile
/
Estados Unidos
/
Venezuela
Instituição/País de afiliação:
Escola Paulista de Medicina/BR
/
Northwestern University Medical School/US
/
Universidad Central de Venezuela/VE
/
Universidad de Antofagasta/CL
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